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O., Adeyemo, S
L-Carnitine converts fat cells into energy by transporting fatty acids into the mitochondria
In nutrient-rich conditions, mTOR remains active, suppressing autophagy initiation, while under stress conditions such as energy deficiency or DNA damage, the activation of AMP-activated protein kinase (AMPK), p53 or inhibition of pathways like PI3K/Akt and ERK reduces mTOR activity, which then releases the inhibition on autophagy and facilitates its initiation (Yang and Klionsky, 2010)
Along with obesity come comorbidities, such as diabetes and high blood pressure, which also affect fertility
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